Biology Corner
Pipe Cleaner Babies
Ever been told you have your father's eyes? How did it happen? Young biologists get a hands-on experience in meiotic gene expression with a fun pairs-based activity. Participants use pipe cleaner chromosomes with trait beads to make...
Howard Hughes Medical Institute
Mapping Genes to Traits in Dogs Using SNPs
Genetic analysis has gone to the dogs! Learners use real DNA information collected from dog saliva to study the relationship between genotypes and phenotypes. They analyze alleles to determine correlations to coat color, length, and...
Howard Hughes Medical Institute
Modeling the Regulatory Switches of the Pitx1 Gene in Stickleback Fish
Gene switches work similarly to light switches in controlling one feature of their environments. Scholars study the Pitx1 gene in a specific type of fish. They learn the different ways this switch controls various body parts and...
Howard Hughes Medical Institute
Patterns in the Distribution of Lactase Persistence
We all drink milk as babies, so why can't we all drink it as adults? Examine the trend in lactase production on the world-wide scale as science scholars analyze and interpret data. Groups create pie charts from the data, place them on a...
Teach Engineering
Show Me the Genes
Give your class a chance to show what they know. In the last installment of a seven-part series, pupils summarize and review what they have learned in the series. They present their solutions for creating a biosensor to detect cancer...
Curated OER
The Effect of Natural Selection on Genes, Traits and Individuals
Rotating through five stations, evolutionary biologists explore the question of how changes in DNA facilitate the changes in a population over time. High-quality, colorful cards of animals, skeletons, skulls, and DNA sequences can all be...
Howard Hughes Medical Institute
The Making of the Fittest: Got Lactase? The Co-evolution of Genes and Culture
Got milk? Only two cultures have had it long enough to develop the tolerance of lactose as an adult. Learn how the responsible genes evolved along with the cultures that have been consuming milk. This rich film is supplied with a few...
Howard Hughes Medical Institute
Winogradsky Columns: Microbial Ecology in the Classroom
Winogradsky columns are ideal for observing the role of bacteria and other microorganisms in an ecosystem. This student activity guide is complete with data tables for observations and analysis questions for processing what was observed....
Howard Hughes Medical Institute
The Making of the Fittest: Natural Selection and Adaptation
The pocket mouse can be light brown like the sands of the desert, or dark brown like the volcanic lava flows that are interspersed throughout New Mexico's Valley of Fire. It seems that predators have weeded out light colored mice in this...
Howard Hughes Medical Institute
HIV Protease Inhibitors
How do doctors fight a virus that's constantly mutating? Show science scholars how we fight HIV using one of its own most fundamental processes through a thoughtful demonstration. The lesson focuses on how protease inhibitors prevent HIV...
Howard Hughes Medical Institute
Stalking the Genetic Basis of a Trait
Need an a-maize-ing lesson to show your class how regulatory genes work? If you use the well-written resource, they'll be all ears! Biology scholars discover the gene responsible for the evolution of the modern-day corn plant through a...
Howard Hughes Medical Institute
Lactose Intolerance: Fact or Fiction
Around the world, about 2/3 of adult humans are lactose intolerant. Scholars work in small groups to discuss a few statements about lactose intolerance. Then, they watch a video on the topic and readdress each statement. Whole-class...
Howard Hughes Medical Institute
Classroom Activities: Stem Cells and Diabetes
How close are we to a cure for diabetes? It seems the cure which has a connection to stem cell research is a possibility! Learners explore the concept of stem cells with an engaging hands-on activity. A PowerPoint presentation provides...
Howard Hughes Medical Institute
Zebrafish and Skin Color
You may not know if that zebrafish in your fish tank is a model citizen—but it is definitely a model organism! What can we learn about ourselves from a tiny zebrafish? Discover more about the polygenic trait of skin color through a...
Howard Hughes Medical Institute
Lactase Persistence: Evidence for Selection
What's the link between lactase persistence and dairy farming? Biology scholars analyze data to find evidence of the connection, then relate this to human adaptation. Working individually and in small groups, learners view short video...
Howard Hughes Medical Institute
Pedigrees and the Inheritance of Lactose Intolerance
What, exactly, causes lactose intolerance? Scholars view a video describing a Finnish study that determined why some people are tolerant while others are intolerant. They then use the data from the study to reenact the experiment and...
Serendip
Genetic Engineering Challenge – How Can Scientists Develop a Type of Rice That Could Prevent Vitamin A Deficiency?
Brown rice contains vitamins B and E, while white rice lasts longer in storage. The availability of rice around the world makes it a great candidate for genetic engineering. Scholars apply their knowledge of genetic engineering to solve...
Serendip
The Molecular Biology of Mutations and Muscular Dystrophy
Different types of mutations cause unique types and degrees of muscular dystrophy. Scholars learn about the types of mutations and the impact on the body. They compare the location of the mutations and draw conclusions about how it is...
Serendip
Using Molecular and Evolutionary Biology to Understand HIV/AIDS and Treatment
HIV mutates rapidly, making treatments challenging to find. Scholars learn about why it mutates so quickly and how scientists race to find treatments. The resource approaches the issue from both a molecular and evolutionary perspective...
Personal Genetics Education Project
Personalized Medicine
Genetics learners read an article and watch a video about personalized medicine and the hope it holds for treating patients more specifically than doctors currently are able to. They research, design, and produce a brochure about the...
University of Pennsylvania
Evolution by Natural Selection
A diagram, data table, and reading passage top this resource. Through it, biology beginners are introduced to the concept of natural selection. They answer some questions and then participate in a simulation using fabric as a habitat and...
Serendip
DNA Structure, Function and Replication
Before a cell replicates, its DNA must replicate. Take advantage of a hands-on guided lesson to teach budding scientists how this happens. Using a set of nucleotide cards, learners become the DNA and work to create matching strands...
National Academy of Sciences
Genetic Disease: Putting DNA to Work
Scientific knowledge of genetic information has grown quickly over the last decade. An interactive lesson has learners research the role of science and medicine in diagnosing and treating genetic disorders. They consider the job of the...
Teach Engineering
Bubbles and Biosensors
Bubbles aren't just for children. In the third installment of a seven-part series, teenagers use bubble solution to create bubbles and observe patterns of refraction on the bubble surfaces. Application of this concept to thin films in...