Oregon State
Using Paper Chromatography
Through the analysis of paper chromatography to separate ink from the pen found at the crime scene, learners analyze the different stains and through calculations determine the thief.
Curated OER
#13 Chromatography is a Gas: An Inquiry-Based Introduction to Gas Chromatography
Advanced chemistry scholars read about gas chromatography as a means of separating mixtures into their components. Then they try the technique on fingernail polish remover. Detailed instructions are provided via a lab sheet for your...
Curated OER
Chromatography Lab
Students discover the components of primary and secondary colors. In this physical science lesson, students create a set up in which water will separate a color into the component colors along a piece of filter paper. Students will then...
Olomana School
Mixtures and Solutions: Paper Chromatography Experiment
Why does some ink bleed through paper, and other ink doesn't? Practice some paper chromatography to separate the colors from a pen with an interactive experiment for middle and high schoolers. Learners use a variety of solutions to track...
Sunlight Cal-Tech
Chromatography of Plant Pigments
Through a hands-on activity, an acetone-spinach solution is pre-made and learners use this solution to separate the pigments found in spinach using chromatography. The comprehensive resource includes an analysis and conclusion questions.
LABScI
The Separation Lab: Candy Colors
There's no better motivator than candy! An engaging activity has pupils explore methods for separating mixtures. A two-part lab first explores methods of separation based on size and magnetism. The second activity introduces learners to...
Curated OER
Lipstick Chromatography/Ink Chromatography
Junior crime scene investigators are instructed in two different chromatography exercises. For female suspects, they separate and compare lipstick pigments. For male suspects, they separate and compare ink samples. A data sheet is...
Curated OER
Recognition and Classification of Mixtures
Immerse your chemistry class in solutions! They melt and compare the mixtures that make up margarine, separate black ink into its component colors, distill ocean saltwater, and practice chromatography with plant pigments. There are eight...
Curated OER
Chromatography
Students use chromatography to separate substances in Kool-Aid, Crayola markers and leaves. In this chromatography lesson plan, students make chromatograms to separate substances in a mixture through absorption. Students find the Rf...
Royal Society of Chemistry
Aspirin—The Wonder of Medicine
What do aspirin and the willow tree have in common? Scholars of chemical synthesis engage in a fascinating reaction to make their own aspirin samples. The lab uses thin layer chromatography analysis, includes stoichiometric calculations,...
Curated OER
Standard One: Lab Design and Appendix A Lab Skills
In this lab design and lab skills worksheet, students answer questions about experimental design including finding variables, determining controls, and graphing data. They answer questions about microscopy and label the parts of a...
Curated OER
Straw Chromatography
Students become acquainted with the principles of liquid chromatography and construct a liquid chromatography column. Students also investigate the effects of different solvents and solvent concentrations in the separation process.
Curated OER
Using Thin Layer Chromatography To Identify amino Acids In Solution
Young scholars will work in groups to design and conduct an experiment to identify amino acids found in an unknown solution. This lesson is taught in three sections: (1) Introduction to chromatography (2) Experimental design session (3)...
Curated OER
Paper Chromatography K-12 Experiment
Young scholars study chromatography and how they can distinguish between the different pigments in a color. For this chromatography lesson students separate a mixture of dyes in soluble ink then record the colors they see.
Curated OER
Using Plant Pigments to Link a Suspect to a Crime
Learners use chromatography to separate plant pigments collected from a fictitious crime scene and suspects. They compare the Rf values of the plant pigments to determine whether the plant pigments found on any of the suspects match the...
Chymist
The Extraction and Identification of Artificial Food Colors
Did you know some food dyes are considered safe while others are considered carcinogenic? During the experiment, young chemists extract artificial food colors from prepared foods. Then, they use chromatography paper to identify which...
Curated OER
Chromatography
Students conduct various experiments on chromatography. In this chemistry lesson, students distinguish among the different types of chromatography methods. They explain how the stationary and mobile phase interact with each other.
Curated OER
Thin Layer Chromatography (TLC)
Students study flavinoids and how they exist in the plant kingdom. In this pigment lesson students complete a lab activity to see how flavinoids move in substances then record their observations.
Curated OER
Column Chromatography
Students research the mechanics of liquid chromatography. In this technology instructional activity, students calculate the concentration of unknown samples. They write a report about their research and lab results.
Curated OER
The Conceptual Theory of Chromatography
High schoolers conduct a lab to determine the best way to separate a variety of mixtures choosing between paper, thin layer and column chromatography. They use chromatography techniques to identify unknown substances and submit a lab...
Curated OER
Chromatography
Learners research types of chromatography and complete chromatography experiments.
Curated OER
Programming the "Rinse Robot"
Experienced chemistry technicians use then layer chromatography to discover how much of a free compound is left after each rinse cycle. Where this could obviously be used as a practice with chromatography technique, it can also be used...
Kenan Fellows
An Analytical Chemist, a Biochemist, an Animal Scientist, and an Oncologist Walk into a Lab...No Joke
Oncology presents multiple opportunities for research and the collaboration of many different types of scientists. Scholars divide into groups and research the history of mass spectrometry, polarity/non-polarity,...
Curated OER
Major Organic Acids in Fruits
Students investigate the organic acids present in a variety of juices. In this organic acids lesson plan, students read about the effects of organic acids in juices. They use paper chromatography to separate out the acids present in a...
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