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Howard Hughes Medical Institute
Genetic Mutations and Disease Interactive
Genetic mutations occur throughout life, from conception to old age, and the timing influences the severity. Young scientists learn about four different mutation times and the diseases that sometimes occur as a result. They observe the...
Howard Hughes Medical Institute
Central Dogma and Genetic Medicine
Scientists work every day to find solutions to genetic diseases. Scholars learn about the process of gene sequencing, mutations, and the results. They explore genetic diseases and therapies to intervene and help and, through case...
Cold Spring Harbor Laboratory
Mutations Are Changes in Genetic Information
A red delicious apple tree with a simple mutation means we now benefit from the existence of golden delicious apples. Learn how simple mutations change genetic information in DNA sequences. Using biographies, videos, and animations,...
CK-12 Foundation
Transcription of DNA to RNA: Making mRNA
Transcription means a written copy but how can DNA write a message? The video explains transcription and translation as they relate to DNA and RNA. Then in the interactive, scholars practice base pairing and answer analysis...
Cold Spring Harbor Laboratory
Some Types of Mutations Are Automatically Repaired
Does natural light damage or repair DNA? Learn the answer discover the scientists who researched the topic with an online interactive. Scholars read through an online animation presenting the content at their own pace. Then, they read...
Howard Hughes Medical Institute
Regulation of the Lactase Gene
All human infants are lactose tolerant, yet some adults are lactose intolerant—why is that? Individuals discover the process of gene mutation through a study of the lactase gene (LCT). They understand the geographic connections,...
Cold Spring Harbor Laboratory
Genes Can Be Moved Between Species
Biotechnology changes lives every day, but how did it all start? Learn about Cohen and Boyer's technique for recombinant DNA and the founding of this new scientific study. Then, scholars use the online interactive to discover how Hanahan...
Howard Hughes Medical Institute
Recent Adaptations in Humans
You've probably spent plenty of time discussing animal adaptations with your young biologists, but what about human adaptations? Explore the evolving traits of humankind through an interactive that combines text and video clips. Scholars...
Howard Hughes Medical Institute
Bacterial Quorum Sensing
The marine bacteria vibrio harveyi helps with DNA repair in humans. Understanding how to manipulate and genetically mutate this bacteria fascinates researchers. Young scientists observe two different mutations, predict the resulting...
Cold Spring Harbor Laboratory
Evolution Begins with the Inheritance of Gene Variations
Connect Mendelian genetics with Darwinian theories. An interactive lesson lets pupils explore how George Shull used research from other scientists to explore genetic variation. The resource outlines the statistical analysis of genetic...
Cold Spring Harbor Laboratory
One Gene Makes One Protein
Very few universities still offer a master's degree in the ecology of grasses, but that was the degree that led George Wells Beadle to an interest in genetics and later a Nobel Prize. Scholars learn about the discoveries of Dr. Beadle...
Howard Hughes Medical Institute
BCR-ABL: Cancer Protein Structure and Function
How do scientists discover treatments for cancer? A presentation and accompanying worksheet explain how one cancer spreads and a theory of how to stop it. It details the trials and relapses after using the medication. Scholars learn...
Curated OER
Albinistic Animals Are Awesome
Are all academicians allured with alliteration? Use this cross-curricular online resource to simultaneously expose your scholars to parts of speech and the genetic mutation causing albinism. Initial context gives students an introduction...
Howard Hughes Medical Institute
Structure and Function of Telomeres
Curing cancer or finding the fountain of youth—the answer may be understanding the structure and function of telomeres. The relationship of telomeres to both aging and cancer have triggered aggressive research. A thorough lesson...
Howard Hughes Medical Institute
RNA Diversity
Messenger RNA, transfer RNA, and ribozymes ... the many faces of RNA. The structure of RNA makes it much more versatile than the very similar DNA. Learners view a slideshow presentation to learn all about the different forms and...
Howard Hughes Medical Institute
RNA Interference
A classic experiment that stumped scientists for years grabs the attention of young scholars. A slideshow presentation explains the experimental discovery of RNA interface. The lesson goes on to explain in detail the function of RNA...
Cold Spring Harbor Laboratory
Living Things Share Common Genes
Everything evolved from a common ancestor, but how did modern plants and animals develop so many more genes? Scholars use an online interactive to learn about the process. They begin to understand common genes with an animation, multiple...
Cold Spring Harbor Laboratory
DNA Is Only the Beginning for Understanding the Human Genome
Mario Capecchi requested funding for a new procedure targeting genes and was rejected. Four years later, after he proved it worked, the NIH apologized and funded his research. Use an online interactive to learn about his research and the...
Cold Spring Harbor Laboratory
Dna Learning Center: Disease & Mutation: How Gleevec Works
Chronic myeloid leukemia is a disease caused by a genetic mutation that gives rise to this abnormal protein molecule. The abnormal protein triggers the bone marrow to release dangerous numbers" of white blood cells. Gleevec, the thin...
University of Utah
University of Utah: Learning Center: learn.genetics: Making Sn Ps Make Sense
Find out how tiny variations in DNA can help scientists predict humans' response to drugs or to disease risk.
University of Utah
University of Utah: Learning Center: Learn Genetics:the Outcome of Mutation
Mutation is a process that changes a DNA sequence. But how does a difference in a gene's DNA sequence (or genotype) lead to a difference in an observable trait (or phenotype)?
Cold Spring Harbor Laboratory
Dolan Dna Learning Center: Disease & Mutation: Tumor Growth
See how cell division is essential for healthy growth of an organism, and how complex genetic mechanisms have evolved to switch cell division on and off at the proper time for normal development. [0:50]
Concord Consortium
The Molecular Logic Database: Mutations: Changing the Genetic Code
Students will learn about the different types of mutations and how they work. They will compare the effect of these different types of mutations in DNA, including nucleotide substitution, nucleotide insertion, and nucleotide deletion....
Cold Spring Harbor Laboratory
Dolan Dna Learning Center: Disease & Mutation: Sickle Cell
A brief overview of Sickle cell anemia, a genetic disease that affects hemoglobin in the blood. [1:30]
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