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Howard Hughes Medical Institute

RNA Interference

For Students 9th - 12th
A classic experiment that stumped scientists for years grabs the attention of young scholars. A slideshow presentation explains the experimental discovery of RNA interface. The lesson goes on to explain in detail the function of RNA...
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Howard Hughes Medical Institute

Explore Your Inner Animals

For Students 6th - 12th Standards
Human bodies prove evolution thanks to our genes, bones, and more. Learning about specific body parts and how they evolved from other species helps individuals better understand the transition species that helped us become who we are today.
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Howard Hughes Medical Institute

Paleoclimate: A History of Change

For Students 9th - 12th Standards
Earth's climate changed drastically throughout the history of the planet, so why do scientists blame humans for recent changes? Observe data covering the history of the planet that proves the natural climate change patterns. Then, learn...
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Howard Hughes Medical Institute

Bacterial Quorum Sensing

For Students 9th - 12th Standards
The marine bacteria vibrio harveyi helps with DNA repair in humans. Understanding how to manipulate and genetically mutate this bacteria fascinates researchers. Young scientists observe two different mutations, predict the resulting...
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Howard Hughes Medical Institute

Neural Control of Walking and Running

For Students 9th - 12th Standards
Physical therapists state that relearning how to walk often motivates stroke and brain injury patients. Researchers spend a great deal of time focused on understanding the neural control required for walking. They pass along that...
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Howard Hughes Medical Institute

Retroviruses and Viral Diversity

For Students 9th - 12th Standards
Eight percent of DNA comes from retroviruses. Learn what sets retroviruses apart from other types of viruses with an presentation that focuses on the differences between viruses with a DNA genome, an RNA genome, and retroviruses. 
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Howard Hughes Medical Institute

Stem-Cell-Based Therapies

For Students 9th - 12th Standards
Currently, stem cell therapies treat more than 80 diseases, and that number grows every year. Individuals learn about some of these therapies and where the stem cells come from. They then focus on the future of stem cell treatments and...
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Howard Hughes Medical Institute

Genetic Switches

For Students 9th - 12th Standards
Is it reasonable for us to alter genes in plants to make them more nutritious and better tasting? Is it reasonable for us to alter genes to make babies smarter or better looking? The human genome contains millions of gene switches for...
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Howard Hughes Medical Institute

Natural and Artificial Selection

For Students 9th - 12th Standards
Many people oppose genetically modified foods yet support selective breeding in dogs. Learn about the similarities and differences through a short presentation that features many video clips. It covers natural selection, artificial...
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Howard Hughes Medical Institute

How the Body Uses Fat

For Students 9th - 12th Standards
Not all fat is bad—eating good fats actually helps with weight loss. Learn how the body uses fat through a 27-slide presentation that breaks down the path fat takes from entering to exiting the body. Understanding why fat is helpful and...
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Howard Hughes Medical Institute

Virochip DNA Microarray

For Students 9th - 12th Standards
Virochips detect and identify viruses at a higher rate than other tests. Show young scientists how Virochips work to identify existing viruses. They analyze results demonstrating mutations or the evolution of viruses and view videos...
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Howard Hughes Medical Institute

BCR-ABL: Cancer Protein Structure and Function

For Students 9th - 12th Standards
How do scientists discover treatments for cancer? A presentation and accompanying worksheet explain how one cancer spreads and a theory of how to stop it. It details the trials and relapses after using the medication. Scholars learn...
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Howard Hughes Medical Institute

The Making of a Theory—Fact or Fiction

For Teachers 9th - 12th Standards
Two scientists, two independent studies, two similar theories! A video lesson presents the work of Charles Darwin and Alfred Wallace that led to their theories on evolution. Scholars then evaluate statements and provide evidence to...
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Howard Hughes Medical Institute

Reading Primary Sources: Darwin and Wallace

For Teachers 9th - 12th Standards
Take your classes back in time. Learners read real historical texts from both Darwin and Wallace as well as an announcement of their findings. Using guiding questions, they make inferences and draw conclusions from the information in the...
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Howard Hughes Medical Institute

Exploring Biomes in Gorongosa National Park

For Teachers 9th - 12th
Diversity in a biome leads to some unique characteristics vital to the natural environment. Young scholars use an interactive map to explore the vegetation and climate of the Gorongosa National Park. They collect climate data to compare...
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Howard Hughes Medical Institute

Living Dinosaurs: Fact or Fiction?

For Teachers 9th - 12th Standards
Are birds descendants of dinosaurs? Learners consider the question as they watch an informative video comparing fossil records of dinosaurs with current species. Following the video, groups ponder the evidence to draw conclusions about...
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Howard Hughes Medical Institute

Creating Chains and Webs to Model Ecological Relationships

For Teachers 9th - 12th
The sustainability of an ecosystem depends on many factors and changes constantly. Young scholars consider these factors as they use a set of cards to create food webs. They review key scientific vocabulary such as predator, prey,...
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Howard Hughes Medical Institute

How Did Dinosaurs Regulate Their Body Temperature?

For Teachers 9th - 12th Standards
Are dinosaurs more like birds or reptiles? Learners put the question to the test by analyzing body temperature data from a 2014 study. With their analysis, they develop a theory about the body temperature regulation of dinosaurs.
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Howard Hughes Medical Institute

Classroom Activities: Planaria Regeneration Activity

For Teachers 9th - 12th
Observe a flatworm as it regenerates its own head. A laboratory exploration asks learners to cut a planaria worm at different locations and then observe it regenerate. Using data collected during the exploration, they make conclusions...
Activity
Howard Hughes Medical Institute

Classroom Activities: Mirror-Tracing Activity

For Teachers 9th - 12th
What does it take to train your brain? Learners explore the question as they experiment with their own memory and motor skills. They attempt to trace an object using a mirror and then score their results over several trials. They then...
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Howard Hughes Medical Institute

The Mosquito Life Cycle Activity

For Teachers 9th - 12th Standards
Understanding the life cycle of a mosquito helps us understand how to prevent the spread of diseases they carry. A lab investigation provides learners with the opportunity to track the two-week life cycle of the mosquito. Scholars make...
Activity
Howard Hughes Medical Institute

Coral Reefs in Hot Water

For Teachers 9th - 12th Standards
Global warming is leaving coral reefs in hot water. What does that mean for their survival? Find out as scholars use authentic satellite data to explore the issue. Learners look for global trends in the data and research the effects the...
Activity
Howard Hughes Medical Institute

Battling Vector-Borne Diseases: Factors That Affect the Mosquito Life Cycle

For Teachers 9th - 12th Standards
Slow the spread of disease by slowing disease carriers in their tracks. Learners explore just how they might accomplish this as they experiment with the life cycle of a mosquito under different conditions. Scholars design and conduct...
Activity
Howard Hughes Medical Institute

Classroom Activities: Pedigree Analysis Activity

For Teachers 9th - 12th
Trace a genetic trait through an entire pedigree. A class activity provides pupils with an opportunity to explore a pedigree tree displaying a specific trait. They draw conclusions from the display and provide recommendations based on...

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