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Howard Hughes Medical Institute
Genetic Mutations and Disease Interactive
Genetic mutations occur throughout life, from conception to old age, and the timing influences the severity. Young scientists learn about four different mutation times and the diseases that sometimes occur as a result. They observe the...
Serendip
The Molecular Biology of Mutations and Muscular Dystrophy
Different types of mutations cause unique types and degrees of muscular dystrophy. Scholars learn about the types of mutations and the impact on the body. They compare the location of the mutations and draw conclusions about how it is...
Curated OER
Selection and Variation in the Egyptian Origami Bird
Using origami paper birds, your biology class will experiment with mutations and natural selection to determine wing position, length, and width. It would be helpful to provide a worksheet to go with the activity that includes a...
Serendip
Evolution of Fur Color in Mice – Mutation, Environment and Natural Selection
Most species of animals include a variety of fur or hair color, but why? Scholars watch a video about a changing environment for mice. As the rocks around them change hues, different colors of mice begin to thrive. Discussion questions...
Serendip
UV, Mutations, and DNA Repair
How effective are cells at repairing UV damage? An inquiry-based lesson has learners experiment with organism by exposing them to various levels of UV light and then examining their DNA after a period of time. Pupils test different...
Howard Hughes Medical Institute
The Making of the Fittest: The Birth and Death of Genes
Adaptations must be made as environments change. This fabulous presentation features Icelandic icefish, a transparent, scaleless specimen that even has colorless blood. Genetics and adaptations concepts are explored as scientists study...
Curated OER
Mutations and Cancer
Young scholars study how cancer cells mutate and affect cell division. In this investigative lesson plan students view a PowerPoint presentation learn the seven warning signs of cancer.
Howard Hughes Medical Institute
Central Dogma and Genetic Medicine
Scientists work every day to find solutions to genetic diseases. Scholars learn about the process of gene sequencing, mutations, and the results. They explore genetic diseases and therapies to intervene and help and, through case...
Curated OER
Allele and Phenotype Frequencies in Rock Pocket Mouse Populations
In the deserts of Arizona and New Mexico, some tiny creatures show just how quickly natural selection can turn a mutation into an advantageous adaptation. Watch a video about rock pocket mice, who show that one small change can make all...
Virginia Department of Education
Genetic Variation and Mutations
Young scientists demonstrate their creativity while completing several activities, to assess genetic variations and mutations. Instructors provide a list of options and scientists choose to write a comic strip, create a book,...
Cold Spring Harbor Laboratory
Mutations Are Changes in Genetic Information
A red delicious apple tree with a simple mutation means we now benefit from the existence of golden delicious apples. Learn how simple mutations change genetic information in DNA sequences. Using biographies, videos, and animations,...
Curated OER
Genes, DNA, and Mutations
With paper DNA patterns, budding biologists model translation and base-pair substitution within sequences. Through these activities, they examine how mutations can result in genetic disorders. The modeling that occurs is an enlightening...
Biology Junction
Mutations
Are you a mutant? Learn about multiple types of mutations with a presentation to discover the answer. Both genes and chromosomes mutate at various points in their life cycles. Slides describe each type and the resulting impact on...
Howard Hughes Medical Institute
Natural Selection and Evolution of Rock Pocket Mouse Populations
Can evolution repeat itself? Scholars analyze amino acid data in two separate populations of mice. They learn that evolution repeats itself, but natural selection prefers some mutations over others in different environments. Analysis...
Curated OER
Mutations and Gene Regulation
Teenaged scientists can use this quiz or study guide to show off their understanding of genetic mutations and their causes; includes short answer, multiple choice, matching, and more.
Curated OER
Mutations and Genetic Change
In this genetic mutations worksheet, students compare and contrast different types of mutations including point mutations, silent mutations, and frameshift mutations. This worksheet has 5 matching, 4 fill in the blank, and 3 short answer...
Curated OER
Mutations
After studying DNA replication and the genetics of inheritance, this slide show is useful for explaining specific mutations that can happen and result in an illness. Sickle cell anemia, and cystic fibrosis are explained on a genetic...
Curated OER
DNA Cut and Paste Activity
Here is a cut and paste activity activity designed for older students. They fill in the blank with information about the composition of DNA, then create a DNA strand with its complimentary nucleotide chain.
Concord Consortium
Mutations
Are some mutations more damaging than others? An engaging simulation encourages scholars to alter DNA through insertion, deletion, and substitution. It then forms resulting amino acids—or not—and the resulting protein—or not—depending on...
Cold Spring Harbor Laboratory
Some Types of Mutations Are Automatically Repaired
Does natural light damage or repair DNA? Learn the answer discover the scientists who researched the topic with an online interactive. Scholars read through an online animation presenting the content at their own pace. Then, they read...
Science 4 Inquiry
"Something Old, Something New..."
Young scientists learn about DNA replication through a video and model creation. They answer analysis questions before exploring the role of mutations and then complete a summative assessment.
Howard Hughes Medical Institute
BCR-ABL: Cancer Protein Structure and Function
How do scientists discover treatments for cancer? A presentation and accompanying worksheet explain how one cancer spreads and a theory of how to stop it. It details the trials and relapses after using the medication. Scholars learn...
Howard Hughes Medical Institute
Natural Selection and the Evolution of Darwin's Finches
Darwin explained the connection between species of finches 150 years before scientists understood DNA. Technology and progressing science proved he was right, yet many struggle to understand how natural selection happens. Scholars use...
Howard Hughes Medical Institute
The Making of the Fittest: Natural Selection and Adaptation
The pocket mouse can be light brown like the sands of the desert, or dark brown like the volcanic lava flows that are interspersed throughout New Mexico's Valley of Fire. It seems that predators have weeded out light colored mice in this...
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