Hi, what do you want to do?
Curated OER
The Effect of Natural Selection on Genes, Traits and Individuals
Rotating through five stations, evolutionary biologists explore the question of how changes in DNA facilitate the changes in a population over time. High-quality, colorful cards of animals, skeletons, skulls, and DNA sequences can all be...
Teach Engineering
Inside the DNA
Get your class to take a closer look at DNA. Pupils conduct research to determine the methods used by scientists to analyze the molecular structure of DNA. The class members investigate different types of molecular imaging along with gel...
Howard Hughes Medical Institute
Using DNA to Explore Lizard Phylogeny
In a fun and interactive two-day lesson, learners sort anole lizard pictures by appearance. Next, they watch a video about the anoles and re-sort based on the information in the video. In addition to physical characteristics, budding...
Lincoln Public Schools
Cell Exploration Activities
Engage young biologists in exploring the mysteries of life with this collection of hands-on activities. Enlisting the help of numerous digital resources, students get an up-close look at the structure of plant and animal...
Howard Hughes Medical Institute
Viral DNA Integration
How do reverse transcriptase inhibitors work? Young virologists examine the function of azidothymidine, a drug doctors use to treat HIV patients, during a hands-on modeling activity. Groups create a strand of DNA from an HIV RNA strand...
Howard Hughes Medical Institute
DNA Profiling Activity
Everyone loves a good mystery ... can your class actually solve one? Partnered pupils take on the role of forensic investigators during a three-part activity focusing on DNA evidence processing. Learners discover the methods used to...
Howard Hughes Medical Institute
Stalking the Genetic Basis of a Trait
Need an a-maize-ing lesson to show your class how regulatory genes work? If you use the well-written resource, they'll be all ears! Biology scholars discover the gene responsible for the evolution of the modern-day corn plant through a...
Howard Hughes Medical Institute
Natural Selection and the Evolution of Darwin's Finches
Darwin explained the connection between species of finches 150 years before scientists understood DNA. Technology and progressing science proved he was right, yet many struggle to understand how natural selection happens. Scholars use...
Serendip
DNA Structure, Function and Replication
Before a cell replicates, its DNA must replicate. Take advantage of a hands-on guided lesson to teach budding scientists how this happens. Using a set of nucleotide cards, learners become the DNA and work to create matching strands...
Serendip
The Molecular Biology of Mutations and Muscular Dystrophy
Different types of mutations cause unique types and degrees of muscular dystrophy. Scholars learn about the types of mutations and the impact on the body. They compare the location of the mutations and draw conclusions about how it is...
Serendip
UV, Mutations, and DNA Repair
How effective are cells at repairing UV damage? An inquiry-based lesson has learners experiment with organism by exposing them to various levels of UV light and then examining their DNA after a period of time. Pupils test different...
Howard Hughes Medical Institute
Winogradsky Columns: Microbial Ecology in the Classroom
Winogradsky columns are ideal for observing the role of bacteria and other microorganisms in an ecosystem. This student activity guide is complete with data tables for observations and analysis questions for processing what was observed....
Serendip
DNA
Get up close and personal with DNA! A two-part hands-on activity has learners extract DNA from a small organism and then their own cheek cells. Scholars then explore DNA replication using questions to guide their analyses.
DiscoverE
Building with Biology
Seeing is believing! Bring DNA to life for young biologists using a simple extraction lab. Individuals extract the DNA from wheat germ, then place it in a microcentrifuge tube for observation. They thread yarn or other material through...
Howard Hughes Medical Institute
HIV Protease Inhibitors
How do doctors fight a virus that's constantly mutating? Show science scholars how we fight HIV using one of its own most fundamental processes through a thoughtful demonstration. The lesson focuses on how protease inhibitors prevent HIV...
Howard Hughes Medical Institute
Niche Partitioning Activity
Dinnertime on the African savanna is a highly choreographed event! Introduce young ecologists to the concept of niche partitioning through a hands-on activity. Pupils research animal behaviors and use data to develop an understanding of...
Macmillan Education
A Wrinkle in Time Discussion and Activity Guide
As you work through Madeleine L'Engle's A Wrinkle in Time, try out some or all of the 20 questions and activities included here. Useful for discussion questions, group assignments, or individual projects, this resource covers plot as...
Serendip
From Gene to Protein via Transcription and Translation
DNA carries the codes for creating just the right protein. A well-designed lesson leads pupils through the process from start to finish and everywhere in between. Guiding questions with supporting video help scholars understand the...
Serendip
Soap Opera Genetics – Genetics to Resolve Family Arguments
Did she cheat on her husband? Did the hospital switch the babies? Should they have children? As much as this sounds like the plot for a soap opera, all of these questions fit into a single lesson on genetics. Scholars read about three...
National Health Museum
Access Excellence: Structure of the Dna Molecule
Read a history of the discovery and study of DNA and its structure. Links to a graphic, other references, and classroom activities.
National Health Museum
Access Excellence: A Visit With Dr. Francis Crick
A transcript of a personal interview with Francis Crick, the co-discoverer of the structure of DNA.
National Health Museum
Access Excellence: Dna Molecule Two Views
Access Excellence provides an excellent graphic showing the structure of the DNA molecule and its components.
Science Buddies
Science Buddies: Use Dna Sequencing to Trace the Blue Whale's Evolutionary Tree
Around 50 million years ago, the mammalian ancestor of today's whales returned to the ocean. In this genomics science fair project, you will use mitochondrial protein sequencing to trace the evolution of whales and identify their closest...
Science Buddies
Science Buddies: Extracting Onion Dna
In this project, you'll learn how to isolate DNA from onion cells, separating it from other cellular components in a manner that still preserves its structure and sequence. In the end, you'll have enough DNA to see with the unaided eye,...