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Gene Jury
DNA Detectives
Police find a man murdered in a local hotel, DNA everywhere, and now they need scholars' help. Budding detectives step into a crime scene playing the roles of victim, suspects, and investigators. They apply knowledge of criminology and...
Serendip
UV, Mutations, and DNA Repair
How effective are cells at repairing UV damage? An inquiry-based lesson has learners experiment with organism by exposing them to various levels of UV light and then examining their DNA after a period of time. Pupils test different...
Curated OER
The Effect of Natural Selection on Genes, Traits and Individuals
Rotating through five stations, evolutionary biologists explore the question of how changes in DNA facilitate the changes in a population over time. High-quality, colorful cards of animals, skeletons, skulls, and DNA sequences can all be...
Serendip
DNA Structure, Function and Replication
Before a cell replicates, its DNA must replicate. Take advantage of a hands-on guided lesson to teach budding scientists how this happens. Using a set of nucleotide cards, learners become the DNA and work to create matching strands...
University of California
Migration of Early Humans: Evidence and Interpretations
While much of prehistory is cloaked in mystery, ancient ancestors left evidence in DNA, languages, and materials from their time. Using photographs of items such as cave paintings and ancient tools, as well as maps of linguistic patterns...
Howard Hughes Medical Institute
Using DNA to Explore Lizard Phylogeny
In a fun and interactive two-day lesson, learners sort anole lizard pictures by appearance. Next, they watch a video about the anoles and re-sort based on the information in the video. In addition to physical characteristics, budding...
Museum of Science
Strawberry DNA
Humans aren't the only ones with DNA—fruit has it too. Using a extraction solution, pupils pull the DNA out of a piece of fruit. Learners crush up a piece of fruit with the solution and filter out the solids. Scholars then add cold...
Teach Engineering
DNA Forensics and Color Pigments
Use food coloring in electrophoresis. The last segment in a four-part series mimics DNA fingerprinting by using chromatography. Teams conduct chromatography on food coloring to find colors that use similar pigmentation in their makeup.
Howard Hughes Medical Institute
Viral DNA Integration
How do reverse transcriptase inhibitors work? Young virologists examine the function of azidothymidine, a drug doctors use to treat HIV patients, during a hands-on modeling activity. Groups create a strand of DNA from an HIV RNA strand...
Howard Hughes Medical Institute
Using DNA to Explore Lizard Phylogeny
On the Caribbean islands, lizards expanded into different niches instead of competing for resources. Scholars discuss and learn from experts in a video how scientists prove the theory. They build phylogenetic trees based on appearances...
Howard Hughes Medical Institute
DNA Profiling Activity
Everyone loves a good mystery ... can your class actually solve one? Partnered pupils take on the role of forensic investigators during a three-part activity focusing on DNA evidence processing. Learners discover the methods used to...
Howard Hughes Medical Institute
Viral DNA Integration
How do viruses hijack our cells to produce more viral particles? Junior immunologists model how viral RNA integrates into a host cell's DNA using pop beads and use interactive tools to explore a virus' genome. The teacher's guide...
National Academy of Sciences
Genetic Disease: Putting DNA to Work
Scientific knowledge of genetic information has grown quickly over the last decade. An interactive lesson has learners research the role of science and medicine in diagnosing and treating genetic disorders. They consider the job of the...
Serendip
DNA
Get up close and personal with DNA! A two-part hands-on activity has learners extract DNA from a small organism and then their own cheek cells. Scholars then explore DNA replication using questions to guide their analyses.
Exploratorium
Secret Codon - Write a Message in DNA
String up a message. Pupils string together colored beads to code a word or short phrase. Each color represents one of the four DNA bases. Using a combination of three bases, learners create an amino acid that stand for each letter of...
Nuffield Foundation
Extracting DNA from Living Things
Help! Someone's trying to take my DNA! An interesting lab experiment has scholars use basic materials to extract DNA. By applying ethanol, cold water, and a protease enzyme, like pineapple juice, they pull strands of DNA from peas,...
Teach Engineering
Inside the DNA
Get your class to take a closer look at DNA. Pupils conduct research to determine the methods used by scientists to analyze the molecular structure of DNA. The class members investigate different types of molecular imaging along with gel...
Serendip
From Gene to Protein via Transcription and Translation
DNA carries the codes for creating just the right protein. A well-designed lesson leads pupils through the process from start to finish and everywhere in between. Guiding questions with supporting video help scholars understand the...
Serendip
The Molecular Biology of Mutations and Muscular Dystrophy
Different types of mutations cause unique types and degrees of muscular dystrophy. Scholars learn about the types of mutations and the impact on the body. They compare the location of the mutations and draw conclusions about how it is...
Serendip
Using Molecular and Evolutionary Biology to Understand HIV/AIDS and Treatment
HIV mutates rapidly, making treatments challenging to find. Scholars learn about why it mutates so quickly and how scientists race to find treatments. The resource approaches the issue from both a molecular and evolutionary perspective...
Macmillan Education
A Wrinkle in Time Discussion and Activity Guide
As you work through Madeleine L'Engle's A Wrinkle in Time, try out some or all of the 20 questions and activities included here. Useful for discussion questions, group assignments, or individual projects, this resource covers plot as...
Howard Hughes Medical Institute
Natural Selection and the Evolution of Darwin's Finches
Darwin explained the connection between species of finches 150 years before scientists understood DNA. Technology and progressing science proved he was right, yet many struggle to understand how natural selection happens. Scholars use...
DiscoverE
Building with Biology
Seeing is believing! Bring DNA to life for young biologists using a simple extraction lab. Individuals extract the DNA from wheat germ, then place it in a microcentrifuge tube for observation. They thread yarn or other material through...
Center for Technology in Teaching and Learning
CSI: The Experience - Family Forensics
Forensic scientists depend on their observation skills to analyze evidence down to the molecular level. Middle and high schoolers practice making observations and predictions with a series of crime scene activities, which includes a...
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