Lesson Plan
Curated OER

Characterization of the Bioluminescence (Lux+) Gene E. coli

For Teachers Higher Ed
Students grow E. coli strain HB101, which contains the plasmid pUCD607 with the bioluminescence (Lux+) gene. The plasmid containing the Lux+ gene is isolated from the E. coli, then characterized by restriction analysis.
Lesson Plan
Curated OER

Beauty: Patterns in Nature

For Teachers 5th - 12th
Students explore the patterns of nature. In this interdisciplinary lesson, students examine beauty in nature and participate in a hands-on simulation that demonstrates how human preferences for beauty have led to an increased frequency...
Lesson Plan
Curated OER

From Gene to Protein Study Guide

For Teachers 12th - Higher Ed
In this biology worksheet, learners review and answer different questions based upon the molecules of DNA and RNA. They look at the specific protein order of the DNA strand and its synthesis.
Lesson Plan
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University of Colorado

Punnett Squares with Piebald Deer

For Teachers 5th - 10th Standards
Explore the science behind Earth's amazing diversity of life with this instructional activity on genetics. Looking at specific traits in piebald deer, carnations, and roan cattle, young scientists use Punnett...
Lesson Plan
Agriculture in the Classroom

Design 'Y'er Genes

For Teachers 9th - 12th Standards
How do changes in DNA affect an organism? Scholars explore chromosomes, genes, DNA, and mutations by modeling the DNA of a strawberry. They build a DNA model, then manipulate it to show how changing the genes transforms the strawberry...
Lesson Plan
MENSA Education & Research Foundation

Peas in a Pod: Genetics

For Teachers 4th - 8th
Can peas have grandparents? Learn about inherited traits and heredity with a set of activities focused on Mendelian genetics. As your class learns about the process of passing traits along in Punnett squares, they take on the role of...
Lesson Plan
Nuffield Foundation

Following Gene Transfer by Conjugation in Bacteria

For Teachers 9th - 12th
After the lab, you'll be able to solve this analogy: Natural selection is to vertical transfer of genes as ___ is to the horizontal transfer of genes. Young biologists conduct an experiment on E. coli bacteria to explore the process of...
Lesson Plan
Curated OER

Cut-Off Genes

For Teachers 9th - 12th
Learners explain the concept of gene sequence analysis. In this gene instructional activity, students draw inferences about phylogenetic similarities of different organisms.
Lesson Plan
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Howard Hughes Medical Institute

Got Lactase? The Co-Evolution of Genes and Culture

For Teachers 8th - 12th Standards
Does the human body evolve as quickly as human culture? With a stellar 15-minute video, explore the trait of lactose intolerance. Only about 1/3 of human adults seem to still have the enzyme lactase and therefore, the ability to digest...
Lesson Plan
Towson University

Mystery of the Crooked Cell

For Teachers 6th - 12th Standards
Can your class solve the Mystery of the Crooked Cell? Junior geneticists collaborate to learn about sickle cell anemia in a fascinating lesson plan. The included materials help them to examine the genetic factors behind the disease...
Lesson Plan
Teach Engineering

See the Genes

For Teachers 10th - 12th
"If you can't explain it simply, you don't understand it well enough" - Albert Einstein. The sixth installment of a seven-part series teaches young scientists about the importance of being able to communicate scientific research and...
Lesson Plan
Curated OER

The Effect of Natural Selection on Genes, Traits and Individuals

For Teachers 9th - 12th Standards
Rotating through five stations, evolutionary biologists explore the question of how changes in DNA facilitate the changes in a population over time. High-quality, colorful cards of animals, skeletons, skulls, and DNA sequences can all be...
Lesson Plan14:52
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Howard Hughes Medical Institute

The Making of the Fittest: Got Lactase? The Co-evolution of Genes and Culture

For Teachers 8th - Higher Ed Standards
Got milk? Only two cultures have had it long enough to develop the tolerance of lactose as an adult. Learn how the responsible genes evolved along with the cultures that have been consuming milk. This rich film is supplied with a few...
Lesson Plan
Curated OER

The Case of Regulation in Cells

For Teachers 9th - 12th Standards
After your biologists have learned about transcription, translation, and gene regulation, they work in a small group to create a poster of a system that serves as an analogy of the gene regulation process. They share their creations with...
Lesson Plan
Curated OER

Gene Puzzles

For Teachers 6th - 8th
Students come to understand that in sexually reproducing organisms, such as humans, typically half of the genes come from each parent. Students examine a fictional pedigree and determine which gene is responsible for a given trait. The...
Lesson Plan
Curated OER

Genes at Work

For Teachers 7th - 12th
Young scholars explore and discuss genetics stories and answer questions about genetic outcomes of offspring. In this genetics lesson, students read genetics stories on a web site. Young scholars use a chart to answer questions regarding...
Lesson Plan
Curated OER

Understanding: The Power of Genes

For Teachers 9th - 12th
Students study genes and the new information on genetics.  In this genes lesson students write essays on their information on genetics. 
Lesson Plan
Teach Engineering

Tell Me Doc—Will I Get Cancer?

For Teachers 10th - 12th
Can you beat the odds of cancer? In the first installment of a seven-part series, future biomedical engineers consider how to detect and diagnose cancer. An article on biosensors provides useful information toward this goal.
Lesson Plan
Curated OER

Reaching Into Your Genes

For Teachers 6th - 12th
Students interact with a video to explore the basis for the science of chromosomes. They perform a chromosomal analysis called a karyotype and explore how seemingly minute errors in chromosomes can lead to devastating illnesses.
Lesson Plan
Howard Hughes Medical Institute

How Novel Icefish Genes Can Improve Human Health

For Teachers 7th - 12th Standards
Designed to accompany the 13-minute video The Making of the Fittest: The Birth and Death of Genes, this handout serves as both a viewing guide during the video and an analysis of how the adaptations of the icefish might help treat...
Lesson Plan
Curated OER

Producing a Strain of E. coli that Glows in the Dark

For Teachers 8th - 12th
Learners observe the experimental process called bacterial transformation and demonstrate phenotype changes in bacteria that have been transformed with an antibiotic-resistance gene and a metabolic marker. They create a luminescent...
Lesson Plan10:25
Howard Hughes Medical Institute

The Making of the Fittest: Natural Selection and Adaptation

For Students 8th - Higher Ed Standards
The pocket mouse can be light brown like the sands of the desert, or dark brown like the volcanic lava flows that are interspersed throughout New Mexico's Valley of Fire. It seems that predators have weeded out light colored mice in this...
Lesson Plan
Howard Hughes Medical Institute

Survival of the Fittest - Variations in the Clam Species Clamys sweetus

For Teachers 6th - 12th Standards
It's not often that you come across a clever laboratory activity that is both imaginative and comprehensive! Using M&M's and Reese's peanut butter candies to represent two different clam species, young biologists test for "relative...
Lesson Plan
Curated OER

Design Yer Genes

For Teachers 7th
Seventh graders explore general structure of and natural changes that occur in DNA strands, and discuss concept of genetic engineering by creating small portion of strawberry chromosome with three genes, modeling naturally occurring...