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Curated OER
cDNA Sequencing By Restriction Project
Young scholars try to confirm the sequence of a given cDNA clone using the WWW tools and traditional restriction analysis. They grow the clone, prep the plasmid, cut the plasmid with restriction enzymes and compare their results to what...
Curated OER
The Cloning of Plasmid and Spinach DNA
Students will first extract genomic DNA from spinach and perform a restriction enzyme digestion on both the spinach DNA and the plasmid using the same restriction enzyme. They then ligate the cut plasmid DNA with the cut spinach DNA in...
Curated OER
DNA Fingerprinting
Ninth graders investigate what restriction enzymes do, and explain how a DNA sample can link a suspect to a crime.
Curated OER
Selecting Soil Organisms in Compost
Students conduct an experiment to demonstrate that many of the enzyme systems needed to break down society's wastes exist in nature among the decomposers in a compost pile. They culture compost bacteria on starch agar to examine the...
Curated OER
Selecting Soil Organisms in Compost
Students demonstrate that many of the enzyme systems needed to break down--and therefore clean up-society's wastes already exist in nature among the decomposers. They select the best starch-munching organisms by altering the environment...
Curated OER
Cloning of Plasmid and Spinach DNA
Students ligate fragments of genomic DNA from spinach into a vector plasmid. They perform a restriction enzyme digestion. Student use a ligated DNA molecule to transform E. coli cells. Students analyze their procedures and outcome of...
Curated OER
Genetics and Molecular Biology
Young scholars create DNA models using colored construction papers. In this biology lesson, students identify enzyme restriction sites. They model how DNA plasmids replicate when taken up by a bacterial cell.
Nuffield Foundation
Investigating the Effect of Temperature on the Activity of Lipase
How does temperature affect lipase activity? Young scholars conduct an experiment to collect data on the interaction of lipase at different temperatures. They add lipase to a solution of milk, sodium carbonate, and phenolphthalein and...
Curated OER
The Great Cafeteria Caper
Students extract DNA from their own hair roots. They run an electrophoresis gel to examine patterns of their DNA along with standard DNA. The experiment is based on a crime scene scenario.
Curated OER
Producing a Strain of E. coli that Glows in the Dark
Students observe the experimental process called bacterial transformation and demonstrate phenotype changes in bacteria that have been transformed with an antibiotic-resistance gene and a metabolic marker. They create a luminescent...
Howard Hughes Medical Institute
The Making of the Fittest: Got Lactase? The Co-evolution of Genes and Culture
Got milk? Only two cultures have had it long enough to develop the tolerance of lactose as an adult. Learn how the responsible genes evolved along with the cultures that have been consuming milk. This rich film is supplied with a few...
Curated OER
Characterization of the Bioluminescence (Lux+) Gene E. coli
Students grow E. coli strain HB101, which contains the plasmid pUCD607 with the bioluminescence (Lux+) gene. The plasmid containing the Lux+ gene is isolated from the E. coli, then characterized by restriction analysis.
Curated OER
The Four Groups of Biologically Important Compounds
This is not they typical set of teacher instructions. It is an organized chart of the important organic compounds. For each, the involved elements, the name of the building block monomers, the names of polymers, extra information, and a...
Curated OER
Living Environment 2004
In this living environment worksheet, learners answer 30 multiple choice questions and 42 short answer questions in preparation for the Regents exam.
Virginia Department of Education
Physical and Chemical Properties of Water
How can you effectively provide detailed concepts of water properties to your high school class in a way they find exciting and challenging at the same time? By letting them play, of course! Through a variety of...
Curated OER
Jeopardy
High schoolers played a game of Jeopardy where there was five categories with five questions each in order to assess the retention of concepts taught over the semester. The categories included: Graphing/Summarizing/ Scientific Method,...
Curated OER
Identification of Gram Negative Bacilli
In this biology worksheet, students review the procedures used to complete the lab activity and then examine the purpose and add the information while answering the questions.
Curated OER
From Gene to Protein Study Guide
In this biology worksheet, students review and answer different questions based upon the molecules of DNA and RNA. They look at the specific protein order of the DNA strand and its synthesis.
Curated OER
Biological Molecules
Ninth graders examine the structure and function of biomolecules. In this food molecule instructional activity, 9th graders will examine various types of biomolecules such as carbohydrates, lipids, proteins, and nucleic...
LABScI
The Digestive System: Where Does Food Go?
Would you believe that your digestive system stretches to five times your height?! Help your pupils to understand this relationship as they work through the laboratory exercise. The first instructional activity of a 12-part series is a...
Curated OER
Energy, Matter, and Organization
Tenth graders review the Energy, Matter, and Organization unit. They have one week to complete an essay. Students must submit a concept map or drawing. The activity is introduces by reading a short story line which presents a simple...
Towson University
Case of the Crown Jewels
Can your biology class crack the Case of the Crown Jewels? Junior forensics experts try their hands at DNA restriction analysis in an exciting lab activity. The lesson introduces the concept of restriction analysis, teaches pipetting and...
Serendip
Using Molecular and Evolutionary Biology to Understand HIV/AIDS and Treatment
HIV mutates rapidly, making treatments challenging to find. Scholars learn about why it mutates so quickly and how scientists race to find treatments. The resource approaches the issue from both a molecular and evolutionary perspective...
Curated OER
DNA on Stick
Students experience a "hands-on" activity to get visual evidence of the physical nature of DNA and the process of DNA purification. They explore one method of chromosomal DNA isolation and DNA extraction.
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