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Howard Hughes Medical Institute
Mendelian Genetics, Probability, Pedigree, and Chi-Square Statistics
People with the sickle cell trait, but not sickle cell disease, find natural protection against malaria. Scholars consider various combinations of genotypes and environmental factors to determine if children might have sickle cell...
Howard Hughes Medical Institute
Weighing the Evidence for a Mass Extinction Part 2: On Land
What can fossils tell us about periods of extinction? Young scholars interpret fossil layers to make conclusions about changes in life during different geological time periods. They analyze the fossils for abundance and diversity as well...
Howard Hughes Medical Institute
The Molecular Evolution of Gene Birth and Death
More than 90 percent of humans' DNA doesn't code for anything! Scholars watch a presentation as they answer questions relating to gene mutations. They read details, watch videos, and view animations supporting the concepts. The questions...
Howard Hughes Medical Institute
Milk—How Sweet Is It?
Have you ever wondered why some people are lactose intolerant? Participants test simulated patients in a hands-on lab activity to find out! They learn about lactose intolerance by performing an experiment, analyzing data, and drawing...
National Wildlife Federation
Fossil Fuel Extraction Activity
Extracting oil is more difficult than many think! Learners work together and get hands-on as they represent oil companies drilling for oil by simulating oil extraction using beans. They identify the challenges faced in using...
Howard Hughes Medical Institute
Climate and Earth Systems
The components of the atmosphere have a significant impact on long-term climate change. Learners begin by analyzing the role of carbon dioxide in the earth systems and how varying the levels would affect those systems—and ultimately...
Howard Hughes Medical Institute
West Nile Virus: Vectors and Hosts Game
The spread of an infectious disease can be a complicated process. Using a game approach, learners reenact the spread of the West Nile virus. They learn the need for the vector in transmitting the disease and how different organisms react...
Howard Hughes Medical Institute
Discovering the Wallace Line
When studying locations of specific species, interesting patterns emerge. Young scholars discover this as they plot the location of specific species on a group of islands. Patterns emerge as they identify the Wallace Line. They then...
Howard Hughes Medical Institute
Pulse Chase Primer: The Meselson-Stahl Experiment
Experimental design can make or break an experiment. Young scholars analyze the pulse-chase analysis procedure by studying the Meselson-Stahl experiment. Using a video presentation, they discover how the pulse-chase analysis led to the...
Howard Hughes Medical Institute
Mapping Genes to Traits in Dogs Using SNPs
Genetic analysis has gone to the dogs! Learners use real DNA information collected from dog saliva to study the relationship between genotypes and phenotypes. They analyze alleles to determine correlations to coat color, length, and...
College Board
2013 AP® Biology Free-Response Questions
AP® free-response questions are often challenging for scholars. Give them practice writing free-response questions using former questions from the AP® Biology exam on topics such as genetic mutations, cellular respiration, evolution, and...
National Wildlife Federation
Pollinator's Journey: Grades K-4
Mimic the struggle of migratory pollinators. Pupils learn about the threats to pollinator species. They go on to enact a play demonstrating the hazards migratory pollinators experience. To finish,...
National Wildlife Federation
Soil Decomposers
The class studies the soil food web that includes earthworms and conduct four experiments using the crawly critters. Individuals determine whether earthworms are sensitive to light, touch, temperature, and acid.
National Wildlife Federation
Spider Sensations
Know that feeling when walking into a spider's web? Feel it from the other end! Scholars learn about the body parts of a spider and the specific spiders known as orb-weavers. Groups play a game to figure out how a spider finds its food...
National Wildlife Federation
Understanding and Measuring School Electronics
Feel the power in turning off electronics. Using energy-monitoring devices, pupils find the amount of energy it takes to power a simple electronic when it is on and when it is off. They then calculate the cost for the entire year for the...
National Wildlife Federation
Hot, Hotter, Hottest: Extreme Weather's Impact on Our Resources
How dry is it? It's so dry, the river only runs twice a week! Through an analysis of maps and discussions, pairs learn about droughts across the United States in the ninth of 12 lessons. They then read about, answer questions, analyze...
Howard Hughes Medical Institute
Vertebrate Circulatorium
When you get to the heart of the matter, you learn a lot about an organism by studying its circulatory system! A perfect resource for a zoology or anatomy class, the simulation gives users a peek inside a variety of vertebrates to...
Howard Hughes Medical Institute
Deep History of Life on Earth
Take it all the way back! Young scientists discover the changes that took place from the time Earth became solid to present day through an interesting interactive. The resource guides users through key events that have shaped our world...
Howard Hughes Medical Institute
Geological History of Oxygen
Earth didn't always have oxygen, so what caused the change that allows humans to live here? Learn about the change in O2 levels throughout geological history through an interactive graph. Each section offers greater detail on the changes...
Howard Hughes Medical Institute
Regulation of the Lactase Gene
All human infants are lactose tolerant, yet some adults are lactose intolerant—why is that? Individuals discover the process of gene mutation through a study of the lactase gene (LCT). They understand the geographic connections,...
Howard Hughes Medical Institute
Creating Phylogenetic Trees from DNA Sequences
How closely are animals related? Check their phylogenetic trees! The use of DNA sequencing altered our understanding of these relationships. Individuals explore and gain a better understanding of how scientists sort, align, and determine...
Howard Hughes Medical Institute
Tissue Regeneration in Animals
Every species regenerates at least one tissue or organ in their bodies. Learn about different regeneration processes in animals. An intriguing presentation specifically discusses starfish, hydras, planaria, salamanders, mice, humans,...
Howard Hughes Medical Institute
Look Who's Coming for Dinner: Selection by Predation
What happens when a new predator comes to town? Learners analyze an experiment that studies the effect of predation on selection. They use real data to draw conclusions about the impact a new predator has on a prey species.
Howard Hughes Medical Institute
Biodiversity and Evolutionary Trees
Compare what shells look like on the outside with what makes that happen on the inside. Scholars begin by sorting an various seashells by their physical characteristics into phylogenetic trees. They then conduct a DNA comparison of...
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