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Howard Hughes Medical Institute
Using DNA to Explore Lizard Phylogeny
In a fun and interactive two-day lesson, learners sort anole lizard pictures by appearance. Next, they watch a video about the anoles and re-sort based on the information in the video. In addition to physical characteristics, budding...
Howard Hughes Medical Institute
Viral DNA Integration
How do viruses hijack our cells to produce more viral particles? Junior immunologists model how viral RNA integrates into a host cell's DNA using pop beads and use interactive tools to explore a virus' genome. The teacher's guide...
Howard Hughes Medical Institute
DNA Profiling Activity
Everyone loves a good mystery ... can your class actually solve one? Partnered pupils take on the role of forensic investigators during a three-part activity focusing on DNA evidence processing. Learners discover the methods used to...
Museum of Science
Strawberry DNA
Humans aren't the only ones with DNA—fruit has it too. Using a extraction solution, pupils pull the DNA out of a piece of fruit. Learners crush up a piece of fruit with the solution and filter out the solids. Scholars then add cold...
Lincoln Public Schools
Cell Exploration Activities
Engage young biologists in exploring the mysteries of life with this collection of hands-on activities. Enlisting the help of numerous digital resources, students get an up-close look at the structure of plant and animal...
Teach Engineering
Inside the DNA
Get your class to take a closer look at DNA. Pupils conduct research to determine the methods used by scientists to analyze the molecular structure of DNA. The class members investigate different types of molecular imaging along with gel...
Serendip
DNA Structure, Function and Replication
Before a cell replicates, its DNA must replicate. Take advantage of a hands-on guided lesson to teach budding scientists how this happens. Using a set of nucleotide cards, learners become the DNA and work to create matching strands...
Teach Engineering
DNA Forensics and Color Pigments
Use food coloring in electrophoresis. The last segment in a four-part series mimics DNA fingerprinting by using chromatography. Teams conduct chromatography on food coloring to find colors that use similar pigmentation in their makeup.
Howard Hughes Medical Institute
Viral DNA Integration
How do reverse transcriptase inhibitors work? Young virologists examine the function of azidothymidine, a drug doctors use to treat HIV patients, during a hands-on modeling activity. Groups create a strand of DNA from an HIV RNA strand...
Nuffield Foundation
Extracting DNA from Living Things
Help! Someone's trying to take my DNA! An interesting lab experiment has scholars use basic materials to extract DNA. By applying ethanol, cold water, and a protease enzyme, like pineapple juice, they pull strands of DNA from peas,...
Howard Hughes Medical Institute
Using DNA to Explore Lizard Phylogeny
On the Caribbean islands, lizards expanded into different niches instead of competing for resources. Scholars discuss and learn from experts in a video how scientists prove the theory. They build phylogenetic trees based on appearances...
Serendip
DNA
Get up close and personal with DNA! A two-part hands-on activity has learners extract DNA from a small organism and then their own cheek cells. Scholars then explore DNA replication using questions to guide their analyses.
Serendip
UV, Mutations, and DNA Repair
How effective are cells at repairing UV damage? An inquiry-based lesson has learners experiment with organism by exposing them to various levels of UV light and then examining their DNA after a period of time. Pupils test different...
Center for Technology in Teaching and Learning
CSI: The Experience - Family Forensics
Forensic scientists depend on their observation skills to analyze evidence down to the molecular level. Middle and high schoolers practice making observations and predictions with a series of crime scene activities, which includes a...
National Academy of Sciences
Genetic Disease: Putting DNA to Work
Scientific knowledge of genetic information has grown quickly over the last decade. An interactive lesson has learners research the role of science and medicine in diagnosing and treating genetic disorders. They consider the job of the...
Macmillan Education
A Wrinkle in Time Discussion and Activity Guide
As you work through Madeleine L'Engle's A Wrinkle in Time, try out some or all of the 20 questions and activities included here. Useful for discussion questions, group assignments, or individual projects, this resource covers plot as...
DiscoverE
Building with Biology
Seeing is believing! Bring DNA to life for young biologists using a simple extraction lab. Individuals extract the DNA from wheat germ, then place it in a microcentrifuge tube for observation. They thread yarn or other material through...
Howard Hughes Medical Institute
Niche Partitioning Activity
Dinnertime on the African savanna is a highly choreographed event! Introduce young ecologists to the concept of niche partitioning through a hands-on activity. Pupils research animal behaviors and use data to develop an understanding of...
Howard Hughes Medical Institute
Ebola: Disease Detectives
How did the Ebola virus first infect humans? Young virologists examine genetic sequences from the 2014 Sierra Leone outbreak to find similarities during a riveting activity. Following similar methods used by MIT and Harvard, partners...
Howard Hughes Medical Institute
Pulse Chase Primer: The Meselson-Stahl Experiment
Experimental design can make or break an experiment. Young scholars analyze the pulse-chase analysis procedure by studying the Meselson-Stahl experiment. Using a video presentation, they discover how the pulse-chase analysis led to the...
University of California
Migration of Early Humans: Evidence and Interpretations
While much of prehistory is cloaked in mystery, ancient ancestors left evidence in DNA, languages, and materials from their time. Using photographs of items such as cave paintings and ancient tools, as well as maps of linguistic patterns...
Howard Hughes Medical Institute
Winogradsky Columns: Microbial Ecology in the Classroom
Winogradsky columns are ideal for observing the role of bacteria and other microorganisms in an ecosystem. This student activity guide is complete with data tables for observations and analysis questions for processing what was observed....
Discovery Education
Blueprint for Life
DNA is the code for all biological traits, both plant and animal. Using an exploratory lesson, learners begin to explore the concept of a biological code by decoding word puzzles. They then extract DNA from plant cells using detergent to...
Howard Hughes Medical Institute
Understanding Variation
Does where we live influence how our bodies express genetic traits? Explore variation in human skin color with an activity that incorporate video and hands-on learning. Individuals model the relationship between phenotypes and genotypes,...