Royal Society of Chemistry
Separating Mixtures: How We Concentrate Natural Materials
Have your class look at a granite specimen and describe what they see. They should note three distinct components. Discuss mixtures with them and how they might be separated, then send them to the lab to figure out how to take apart five...
Curated OER
#13 Chromatography is a Gas: An Inquiry-Based Introduction to Gas Chromatography
Advanced chemistry scholars read about gas chromatography as a means of separating mixtures into their components. Then they try the technique on fingernail polish remover. Detailed instructions are provided via a lab sheet for your...
LABScI
The Separation Lab: Candy Colors
There's no better motivator than candy! An engaging activity has pupils explore methods for separating mixtures. A two-part lab first explores methods of separation based on size and magnetism. The second activity introduces learners to...
Curated OER
Recognition and Classification of Mixtures
Immerse your chemistry class in solutions! They melt and compare the mixtures that make up margarine, separate black ink into its component colors, distill ocean saltwater, and practice chromatography with plant pigments. There are eight...
Olomana School
Mixtures and Solutions: Paper Chromatography Experiment
Why does some ink bleed through paper, and other ink doesn't? Practice some paper chromatography to separate the colors from a pen with an interactive experiment for middle and high schoolers. Learners use a variety of solutions to track...
Curated OER
Separation of a Complex Mixture
Students develop a method to separate different types of mixtures. For this chemistry lesson, students model the steps in the scientific method. They perform the experiment and analyze data.
Curated OER
Lipstick Chromatography/Ink Chromatography
Junior crime scene investigators are instructed in two different chromatography exercises. For female suspects, they separate and compare lipstick pigments. For male suspects, they separate and compare ink samples. A data sheet is...
Virginia Department of Education
Laboratory Safety and Skills
Avoiding lab safety rules will not give you super powers. The lesson opens with a demonstration of not following safety rules. Then, young chemists practice their lab safety while finding the mass of each item in a mixture and trying to...
Curated OER
Chromatographic Separation of Methylene Blue and Sodium Fluorescein
Students determine the best solvent system for separating a methylene blue/sodium fluorescein mixture by thin layer chromatography. They conduct an initial TLC separation using ethanol and a different solvent mixture and analyze the data...
Curated OER
Lab: Percent of Composition of KClO3
Students find the percent of oxygen in potassium chlorate. In this percent composition lesson plan, students heat a solution of potassium chlorate using a catalyst, manganese dioxide, to decompose the potassium chlorate and release...
Curated OER
#16 Separation Science Lab
High schoolers in this inquiry-based experiment, put in the role of a method development chemist. The scenario they are given is that a train wreck has occurred resulting in a chemical spill. Students are told that the spill mixture...
Curated OER
Chromatography Lab
Students discover the components of primary and secondary colors. In this physical science lesson, students create a set up in which water will separate a color into the component colors along a piece of filter paper. Students will then...
Curated OER
Programming the "Rinse Robot"
Experienced chemistry technicians use then layer chromatography to discover how much of a free compound is left after each rinse cycle. Where this could obviously be used as a practice with chromatography technique, it can also be used...
Cornell University
Chemical Reactions
Investigate the Law of Conservation of Mass through a lab exploration. Individuals combine materials to initiate chemical reactions. They monitor for signs of reactions and measure the masses before and after the reactions for comparison.
Curated OER
Paper Chromatography K-12 Experiment
Students study chromatography and how they can distinguish between the different pigments in a color. In this chromatography lesson students separate a mixture of dyes in soluble ink then record the colors they see.
Curated OER
The Effects of Temperature on Chemical Mixtures
Students explore chemical cahnges and the effect of temperature on chemical mixturees, They make observations of the behavior and appearance of certain chemical mixtures and reactions.
Curated OER
Rainbow Electrophoresis Lab
Students are introduced to the principles of gel electrophoresis. They practice loading gels and pipetting. In this laboratory activity, food color is separated into constituent pigments. The lab can be run with standard electrophoresis...
Curated OER
Thin Layer Chromatography (TLC) Separation of Plant Pigments - Chlorophyll, Carotene
Students use TLC separations to identify various substances. In this chlorophyll lesson students separate pigments found in different plants.
Curated OER
Enzyme Labs Using Jello
High schoolers test for the presence of enzymes in fruit and the specificity of those enzymes, as well as to identify and show the susceptibility of enzymes to certain environmental factors (temperature and pH) originating in the...
Curated OER
Exploring the Scientific Method: Separation of a Complex Mixture
Students work in teams to use the scientific method to separate complex mixtures into pure components.
Sunlight Cal-Tech
Chromatography of Plant Pigments
Through a hands-on activity, an acetone-spinach solution is pre-made and learners use this solution to separate the pigments found in spinach using chromatography. The comprehensive resource includes an analysis and conclusion questions.
Curated OER
Chromatography
Students use chromatography to separate substances in Kool-Aid, Crayola markers and leaves. In this chromatography lesson plan, students make chromatograms to separate substances in a mixture through absorption. Students find the Rf...
Curated OER
Kinetics of acetone iodination
For this chemistry worksheet, students examine the given concept in order to apply in the laboratory setting. The sheet includes in depth background information.
Curated OER
The Conceptual Theory of Chromatography
Students conduct a lab to determine the best way to separate a variety of mixtures choosing between paper, thin layer and column chromatography. They use chromatography techniques to identify unknown substances and submit a lab report on...