Activity
Howard Hughes Medical Institute

Tracking Genetically Modified Mosquitoes

For Teachers 9th - 12th Standards
What's that buzzing in your ear? An insightful lesson about genetically modified mosquitoes! Partnered pupils explore the creation, release, and monitoring of mosquitoes designed to reduce the mosquito population. After watching a video,...
Activity
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Cherokee County Schools

Dragon Genetics

For Teachers 9th - 12th Standards
It's alive! Turn young biologists into mad scientists with this engaging genetics activity. Using their knowledge of chromosomes and genes, students create dragons with unique sets of traits,...
Activity
Howard Hughes Medical Institute

Understanding Variation

For Teachers 9th - Higher Ed Standards
Does where we live influence how our bodies express genetic traits? Explore variation in human skin color with an activity that incorporate video and hands-on learning. Individuals model the relationship between phenotypes and genotypes,...
Lesson Plan
Curated OER

The Effect of Natural Selection on Genes, Traits and Individuals

For Teachers 9th - 12th Standards
Rotating through five stations, evolutionary biologists explore the question of how changes in DNA facilitate the changes in a population over time. High-quality, colorful cards of animals, skeletons, skulls, and DNA sequences can all be...
Activity
Biology Corner

Pipe Cleaner Babies

For Students 9th - 12th
Ever been told you have your father's eyes? How did it happen? Young biologists get a hands-on experience in meiotic gene expression with a fun pairs-based activity. Participants use pipe cleaner chromosomes with trait beads to make...
Activity
Howard Hughes Medical Institute

Classroom Activities: Pedigree Analysis Activity

For Teachers 9th - 12th
Trace a genetic trait through an entire pedigree. A class activity provides pupils with an opportunity to explore a pedigree tree displaying a specific trait. They draw conclusions from the display and provide recommendations based on...
Lesson Plan
Serendip

Soap Opera Genetics – Genetics to Resolve Family Arguments

For Teachers 9th - 12th Standards
Did she cheat on her husband? Did the hospital switch the babies? Should they have children? As much as this sounds like the plot for a soap opera, all of these questions fit into a single lesson on genetics. Scholars read about three...
Activity
Howard Hughes Medical Institute

Mendelian Genetics, Probability, Pedigree, and Chi-Square Statistics

For Teachers 9th - 12th Standards
People with the sickle cell trait, but not sickle cell disease, find natural protection against malaria. Scholars consider various combinations of genotypes and environmental factors to determine if children might have sickle cell...
Activity
Howard Hughes Medical Institute

Stalking the Genetic Basis of a Trait

For Teachers 9th - 12th Standards
Need an a-maize-ing lesson to show your class how regulatory genes work? If you use the well-written resource, they'll be all ears! Biology scholars discover the gene responsible for the evolution of the modern-day corn plant through a...
Activity
Howard Hughes Medical Institute

Using Genetic Crosses to Analyze a Stickleback Trait

For Teachers 9th - 12th Standards
Two fish appear different, but how do scientists determine their genotypes? Scholars practice performing test crosses to determine the genotypes of fish given their phenotypes. They answer in-depth comprehension questions and complete...
Activity
Howard Hughes Medical Institute

Mapping Genes to Traits in Dogs Using SNPs

For Teachers 9th - 12th
Genetic analysis has gone to the dogs! Learners use real DNA information collected from dog saliva to study the relationship between genotypes and phenotypes. They analyze alleles to determine correlations to coat color, length, and...
Activity
Howard Hughes Medical Institute

Developing an Explanation for Mouse Fur Color

For Teachers 7th - 12th Standards
Whether or not you think mice are nice, you'll love the colorful activity! Scholars examine evidence for evolution in the rock pocket mouse through video, discussion, and collaborative work. Learners watch a video regarding variation in...
Activity
Discovery Education

Blueprint for Life

For Teachers 6th - 8th
DNA is the code for all biological traits, both plant and animal. Using an exploratory lesson, learners begin to explore the concept of a biological code by decoding word puzzles. They then extract DNA from plant cells using detergent to...
Activity
Howard Hughes Medical Institute

Zebrafish and Skin Color

For Teachers 9th - Higher Ed
You may not know if that zebrafish in your fish tank is a model citizen—but it is definitely a model organism! What can we learn about ourselves from a tiny zebrafish? Discover more about the polygenic trait of skin color through a...
Activity
Howard Hughes Medical Institute

The Teosinte Hypothesis

For Teachers 9th - 12th Standards
Don't want to sound corny, but your class will be a-maize-d by an engaging activity! Explore the history of the modern corn plant through a video and Punnett squares. Junior genetics experts get hands-on experience with actual research...
Activity
Howard Hughes Medical Institute

Biodiversity and Evolutionary Trees

For Teachers 9th - 12th
Compare what shells look like on the outside with what makes that happen on the inside. Scholars begin by sorting an various seashells by their physical characteristics into phylogenetic trees. They then conduct a DNA comparison of...
Activity
Serendip

Genetics Vocabulary Review Game

For Students 9th - 12th
Taboo, anyone?! A vocabulary review lesson asks learners to give their partners clues to help them guess the target word. The catch? There are words that are taboo. If they use the prohibited words, they don't get credit if partners...
Activity
Howard Hughes Medical Institute

Molecular Genetics of Color Mutations in Rock Pocket Mice

For Teachers 9th - 12th Standards
Can you identify mutations just by viewing DNA sequences? Scholars apply prior knowledge of DNA sequences to do just that in an engaging activity. They transcribe and translate genes, thus identifying the locations of mutations. Then,...
Lesson Plan
Serendip

Should States Repeal Their Laws Banning First Cousin Marriage?

For Teachers 9th - 12th Standards
Around half of the states in the US ban first cousin marriage, but does science support that ban? Scholars work through genetic analysis of the risks to understand if more states should ban the practice—or if some should remove it. They...
Activity
Howard Hughes Medical Institute

Pedigrees and the Inheritance of Lactose Intolerance

For Teachers 9th - 12th Standards
What, exactly, causes lactose intolerance? Scholars view a video describing a Finnish study that determined why some people are tolerant while others are intolerant. They then use the data from the study to reenact the experiment and...
Lesson Plan
Serendip

DNA

For Teachers 9th - 12th
Get up close and personal with DNA! A two-part hands-on activity has learners extract DNA from a small organism and then their own cheek cells. Scholars then explore DNA replication using questions to guide their analyses.
Activity
Howard Hughes Medical Institute

Patterns in the Distribution of Lactase Persistence

For Teachers 9th - 12th Standards
We all drink milk as babies, so why can't we all drink it as adults? Examine the trend in lactase production on the world-wide scale as science scholars analyze and interpret data. Groups create pie charts from the data, place them on a...
Lesson Plan
Serendip

The Molecular Biology of Mutations and Muscular Dystrophy

For Teachers 9th - 12th
Different types of mutations cause unique types and degrees of muscular dystrophy. Scholars learn about the types of mutations and the impact on the body. They compare the location of the mutations and draw conclusions about how it is...
Activity
Howard Hughes Medical Institute

Got Lactase? Blood Glucose Data Analysis

For Teachers 9th - 12th Standards
Many physicals include a blood glucose test, but what are doctors actually testing? Scholars graph and interpret blood glucose data, allowing them to observe the differences in lactase persistence and draw conclusions. They then connect...

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