Serendip
The Molecular Biology of Mutations and Muscular Dystrophy
Different types of mutations cause unique types and degrees of muscular dystrophy. Scholars learn about the types of mutations and the impact on the body. They compare the location of the mutations and draw conclusions about how it is...
Howard Hughes Medical Institute
Lactose Intolerance: Fact or Fiction
Around the world, about 2/3 of adult humans are lactose intolerant. Scholars work in small groups to discuss a few statements about lactose intolerance. Then, they watch a video on the topic and readdress each statement. Whole-class...
Howard Hughes Medical Institute
Using Genetic Crosses to Analyze a Stickleback Trait
Two fish appear different, but how do scientists determine their genotypes? Scholars practice performing test crosses to determine the genotypes of fish given their phenotypes. They answer in-depth comprehension questions and complete...
Howard Hughes Medical Institute
Modeling the Regulatory Switches of the Pitx1 Gene in Stickleback Fish
Gene switches work similarly to light switches in controlling one feature of their environments. Scholars study the Pitx1 gene in a specific type of fish. They learn the different ways this switch controls various body parts and...
Howard Hughes Medical Institute
Mendelian Genetics, Probability, Pedigree, and Chi-Square Statistics
People with the sickle cell trait, but not sickle cell disease, find natural protection against malaria. Scholars consider various combinations of genotypes and environmental factors to determine if children might have sickle cell...
Serendip
Soap Opera Genetics – Genetics to Resolve Family Arguments
Did she cheat on her husband? Did the hospital switch the babies? Should they have children? As much as this sounds like the plot for a soap opera, all of these questions fit into a single lesson on genetics. Scholars read about three...
Serendip
Mitosis, Meiosis and Fertilization Vocabulary Review Taboo Game
Can you describe a gamete without using the words sperm or egg? Scholars play a vocabulary review game where they try to get other players to guess their words. Each card has the target word as well as two related words they must not...
Serendip
From Gene to Protein via Transcription and Translation
DNA carries the codes for creating just the right protein. A well-designed lesson plan leads pupils through the process from start to finish and everywhere in between. Guiding questions with supporting video help scholars understand the...
Serendip
DNA Structure, Function and Replication
Before a cell replicates, its DNA must replicate. Take advantage of a hands-on guided lesson to teach budding scientists how this happens. Using a set of nucleotide cards, learners become the DNA and work to create matching strands...
Serendip
DNA
Get up close and personal with DNA! A two-part hands-on activity has learners extract DNA from a small organism and then their own cheek cells. Scholars then explore DNA replication using questions to guide their analyses.
Howard Hughes Medical Institute
Explore Your Inner Animals
Human bodies prove evolution thanks to our genes, bones, and more. Learning about specific body parts and how they evolved from other species helps individuals better understand the transition species that helped us become who we are today.
Kenan Fellows
Unit 3: Genetic Variation
What happens when genes change? Junior genetic investigators examine the effects of mutation in the third unit of a four-part Biotechnology series. Individuals discover the types of mutations through a series of PowerPoints, then partner...
Kenan Fellows
Unit 2: DNA Analysis
Ever wonder how they solve those mysterious murders in TV crime dramas? The second of four units in a Biotechnology series introduces scholars to the many methods of DNA analysis. Pupils create and run their own gel electrophoresis...
Howard Hughes Medical Institute
How to Analyze DNA Microarray Data
Unravel the complexities of DNA research. Analyzing DNA data can be a daunting, time-consuming task; however, as the lesson explains, an interactive importance of the research outweighs its complexities. The presentation breaks down the...
Howard Hughes Medical Institute
Structure and Function of Telomeres
Curing cancer or finding the fountain of youth—the answer may be understanding the structure and function of telomeres. The relationship of telomeres to both aging and cancer have triggered aggressive research. A thorough lesson...
Howard Hughes Medical Institute
RNA Interference
A classic experiment that stumped scientists for years grabs the attention of young scholars. A slideshow presentation explains the experimental discovery of RNA interface. The lesson goes on to explain in detail the function of RNA...
Howard Hughes Medical Institute
RNA Diversity
Messenger RNA, transfer RNA, and ribozymes ... the many faces of RNA. The structure of RNA makes it much more versatile than the very similar DNA. Learners view a slideshow presentation to learn all about the different forms and...
Howard Hughes Medical Institute
Viral DNA Integration
How do reverse transcriptase inhibitors work? Young virologists examine the function of azidothymidine, a drug doctors use to treat HIV patients, during a hands-on modeling activity. Groups create a strand of DNA from an HIV RNA strand...
Howard Hughes Medical Institute
Alzheimer’s Disease: Piecing Together the Evidence
5.7 million Americans live with Alzheimer's disease. With limited funding for research, where should scientists focus? Young scientists learn about current research and create their own questions. They then decide the best areas to focus...
Howard Hughes Medical Institute
Virus Explorer
Most pupils know about the flu, HIV, and other viruses, but they don't know what each actually looks like. This interactive shows their relative size, structure, and allows for comparisons. It stresses the similarities and differences...
Howard Hughes Medical Institute
Central Dogma and Genetic Medicine
Scientists work every day to find solutions to genetic diseases. Scholars learn about the process of gene sequencing, mutations, and the results. They explore genetic diseases and therapies to intervene and help and, through case...
Howard Hughes Medical Institute
Stalking the Genetic Basis of a Trait
Need an a-maize-ing lesson to show your class how regulatory genes work? If you use the well-written resource, they'll be all ears! Biology scholars discover the gene responsible for the evolution of the modern-day corn plant through a...
Howard Hughes Medical Institute
Understanding Variation
Does where we live influence how our bodies express genetic traits? Explore variation in human skin color with an activity that incorporate video and hands-on learning. Individuals model the relationship between phenotypes and genotypes,...
Howard Hughes Medical Institute
Viral DNA Integration
How do viruses hijack our cells to produce more viral particles? Junior immunologists model how viral RNA integrates into a host cell's DNA using pop beads and use interactive tools to explore a virus' genome. The teacher's guide...